E0771
Sigma
Monoclonal Anti-Endothelin antibody produced in mouse
clone ET-1/58, ascites fluid
| MDL number: | MFCD00163554 |
Description
| Immunogen | synthetic human endothelin-1, conjugated to KLH. |
| Specificity | The antibody reacts in radioimmunoassay (RIA) with endothelin-1 (ET-1), (human, porcine), endothelin-2 (ET-2) (human), and endothelin-3 (ET-3) (human, rat). Cross-reactivity is observed with sarafotoxin S6c and β-endothelin (mouse). No cross-reactivity is detected with big-endothelin 38 (human), big-endothelin 39 (rat), atrial natriuretic peptide (human) or angiotensin I (human). |
Properties
| antibody form | ascites fluid |
| clone | ET-1/58 (monoclonal) |
| contains | 15 mM sodium azide |
| species reactivity | human, pig, rat |
| application(s) | dot blot: suitable |
| immunohistochemistry (frozen sections): suitable using acetone-fixed sections | |
| indirect ELISA: 1:1,000 | |
| microarray: suitable | |
| radioimmunoassay: 1:20,000 | |
| isotype | IgG2a |
| Gene Information | human ... EDN1(1906) |
| rat ... Edn1(24323) | |
| shipped in | dry ice |
| storage temp. | −20°C |
Safety
| WGK Germany | 3 |
Related Products
| Array | XP725, Panorama® Antibody Microarray - XPRESS Profiler725 Kit |
References
| reference | Cain, B., et al., Early transcriptional effects of aldosterone in a mouse inner medullary collecting duct cell line. Am. J. Physiol. Renal Physiol. 285, F664-F673, (2003) Abstract |
